Medicament containing an effector of the glutathione...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/385 (2006.01) A61K 31/137 (2006.01) A61K 31/401 (2006.01) A61K 31/403 (2006.01) A61P 13/12 (2006.01)

Patent

CA 2446673

The invention relates to a medicament containing an effector of the glutathione metabolism together with .alpha.-lipoic acid, its salts and/or prodrugs as a combined preparation for the simultaneous, separate or time- controlled treatment of a defective thiol-disulfide status in kidney replacement therapy and of clinical characteristics, which indicate a disorder of the thiol-disulfide status of immunocytes. The correction of a defective thiol metabolism is of fundamental importance as a basic therapy for treating a large number of diseases of different origin, in particular however in circumstances requiring an essential kidney replacement therapy.

L'invention concerne un médicament renfermant un effecteur du métabolisme du glutathion conjointement avec de l'acide .alpha.-lipoïque, ses sels et/ou des promédicaments, en tant que préparation combinée pour le traitement simultané, séparé, ou à temps contrôlé, d'une anomalie de l'état thiol-disulfure, révélateur d'un trouble de l'état thiol-disulfure des immunocytes. La correction d'un métabolisme de thiol perturbé est d'une importance fondamentale comme thérapie de base pour le traitement d'un grand nombre de maladies d'origines différentes, principalement dans les conditions d'une thérapie nécessaire de remplacement du rein.

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