Medicament for prevention and treatment of dermatitis having...

Details Medicament for prevention and treatment of dermatitis having... Medicament for prevention and treatment of dermatitis having...

A - Human Necessities

61

K

A61K 31/517 (2006.01) A61P 17/00 (2006.01)

Patent

CA 2368382

Preventive or therapeutic drugs for dermatitises accompanied with dimorphic inflammatory reactions and those caused by repeated exposure to antigens, which inhibit the progression of such dermatitises and are so safe by virtue of their being free from adverse effects as to bring about enhancement in the quality of daily life of a patient. Specifically, remedies for the above dermatitisescontaining chymase inhibitors as the active ingredient, wherein the chymase inhibitors are quinazoline derivatives of the general formula (I) or (II) or pharmacologically acceptable salts thereof.

Médicaments préventifs ou thérapeutiques destinés à traiter des dermatites accompagnées de réactions inflammatoires en deux phases et celles provoquées par l'exposition répétée à des antigènes. Lesdits médicaments inhibent la progression de ces dermatites, et sont sûrs du fait qu'ils sont exempts d'effets secondaires, améliorant ainsi la qualité de vie du patient. La présente invention concerne spécifiquement des remèdes contre les dermatites susmentionnées, qui contiennent en tant que principe actif des inhibiteurs de chymase. Lesdits inhibiteurs de chymase sont des dérivés de quinazoline de formule générale (I) ou (II) ou des sels pharmacologiquement acceptables desdits dérivés.

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