Medicament for prevention or treatment of various diseases...

A - Human Necessities – 61 – K

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A61K 31/517 (2006.01) A61P 37/08 (2006.01) C07D 239/96 (2006.01)

Patent

CA 2365606

A medicament for the prevention or treatment of diseases involving an increase of eosinophils having a chymase inhibitor, as its effective ingredient, which is a safe medicament for the prevention or treatment of diseases accompanied with an increase in eosinophils, which suppresses the progress of the condition, prevents progress of complications, and improves the quality of life of the patient, wherein a quinazoline derivative having the formula (I): (See formula I) or a pharmaceutically acceptable salt thereof is included.

Médicaments préventifs ou thérapeutiques qui inhibent la progression des maladies associées à l'éosinophilie, tout en empêchant la progression de divers complications, et qui sont sûrs du fait qu'ils sont exempts d'effets secondaires, améliorant ainsi la qualité de vie du patient. La présente invention concerne spécifiquement des médicaments préventifs ou thérapeutiques contre les maladies associées à l'éosinophilie, qui contiennent en tant que principe actif des inhibiteurs de chymase. Lesdits inhibiteurs sont des dérivés de quinazoline de formule générale (I) ou des sels pharmacologiquement acceptables desdits dérivés.

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