Medicament vehicle for the controlled administration of an...

Details Medicament vehicle for the controlled administration of an... Medicament vehicle for the controlled administration of an...

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 9/10 (2006.01) A61K 9/14 (2006.01) A61K 9/51 (2006.01) A61K 31/19 (2006.01) A61K 38/00 (2006.01) A61K 47/44 (2006.01)

Patent

CA 2372461

The invention relates to particulate vehicles of active agents which are in a solid state of aggregation at room temperature (20 ~C) and which consist of a pure lipid-medicament conjugate or of a mixture of several lipid-medicament conjugates in the form of a particle matrix. The bond in the lipid-medicament conjugate is effected by covalent bonds, electrostatic interactions, dipole moments, dispersion forces, ion interactions, hydrogen bridges and/or hydrophobic interactions.

L'invention concerne des excipients particulaires qui se trouvent à l'état d'agrégat solide à température ambiante (20 ·C) et sont constitués d'un conjugué pur lipide-substance pharmaceutique ou d'un mélange de plusieurs de ces conjugués en tant que matrice particulaire. La liaison dans ledit conjugué est provoquée par des liaisons covalentes, des interactions électrostatiques, des moments dipolaires, des forces de dispersion, des interactions ioniques, des ponts hydrogène et/ou des interactions hydrophobes.

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