Medicaments

Details Medicaments Medicaments

A - Human Necessities

61

K

A61K 38/17 (2006.01) A61P 17/00 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2656965

There is provided the use of WNT5A, or a therapeutically effective fragment or derivative thereof, in the preparation of a medicament for use in the prevention, reduction or inhibition of scarring. There is also provided the use of WNT5A, or a therapeutically effective fragment or derivative thereof, in the preparation of a medicament for use in the prevention and/or treatment of a fibrotic disorder. Further aspects relate to methods by which scarring may be prevented, reduced or inhibited, and by which fibrotic disorders may be prevented and/or treated. Therapeutically effective amounts of WNT5A, or its fragments or derivatives, that may be used in the medicaments or methods of the invention are also provided.

L'invention concerne l'utilisation de WNT5A, ou d'un fragment ou d'un dérivé thérapeutiquement efficace correspondant, dans la préparation d'un médicament destiné à prévenir, réduire ou inhiber la formation d'une cicatrice. L'invention concerne également l'utilisation de WNT5A, ou d'un fragment ou d'un dérivé thérapeutiquement efficace correspondant, dans la préparation d'un médicament destiné à prévenir et/ou traiter un trouble fibrotique. D'autres aspects concernent des méthodes permettant de prévenir, réduire ou inhiber la formation d'une cicatrice, ainsi que de prévenir et/ou traiter des troubles fibrotiques. L'invention se rapporte en outre à des doses thérapeutiquement efficaces de WNT5A, ou de ses fragments ou dérivés, utilisables dans les médicaments ou les méthodes susmentionnés.

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