Medicaments having controlled release of the active compound

Details Medicaments having controlled release of the active compound Medicaments having controlled release of the active compound

A - Human Necessities

61

K

167/164

A61K 47/38 (2006.01) A61K 9/50 (2006.01) A61K 31/44 (2006.01) A61K 47/30 (2006.01)

Patent

CA 2009736

Medicaments having controlled release of the active compound A B S T R A C T Controlled release medicament pellets comprising a) a core which contains as active ingredient a compound of the formula Image or a compound from the group of 3-(4-fluorophenylsulphon amido)-1,2,3,4-tetrahydro-9-carbazole propanoic acid or 2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-1,2-benziso- thiazol-3(2H)-one 1,1-dioxide monohydrochloride, an intensive disintegrating agent, a wetting agent and a binder, b) a double layer which controls release comprising (b1) an acrylic-based outer undigestible water-permeable lacquer layer, and (b2) an inner jacket layer comprising a hydrophobic additive and hydroxypropylcellulose of type M or H. Le A 26 708

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