C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/220, 260/242
C07D 473/04 (2006.01) A61K 31/52 (2006.01) C07C 29/10 (2006.01) C07C 31/42 (2006.01) C07D 303/08 (2006.01) C07D 317/16 (2006.01) C07D 317/20 (2006.01) C07D 473/06 (2006.01) C07D 473/08 (2006.01)
Patent
CA 1286292
Abstract of the Disclosure: Compounds of the formula Image (I) wherein one of the radicals R1, R2 or R3 denotes a straight-chain alkyl group having 4 to 8 C atoms and two vicinal hydroxyl groups in the .omega.,.omega.1 or .omega.-1,.omega.-2 positions and the two other radicals represent straight- chain or branched alkyl groups having up to 12 C atoms in the position of R1 and R3 and up to 4 C atoms in the position of R2, the total of C atoms in these two alkyl substituents being a maximum of 14, are prepared by oxidation of the corresponding alkenylxanthines and by alkylation with compounds which introduce the dihyd- roxyalkyl radical or a precursor thereof. The dihydroxy- alkyldialkylxanthines are suitable for the treatment of obstructive respiratory tract diseases.
412172
Anagnostopulos Hiristo
Furrer Harald
Gebert Ulrich
Hinze Heinz-Joachim
Anagnostopulos Hiristo
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Furrer Harald
Gebert Ulrich
Hinze Heinz-Joachim
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