Medicinal aerosol compositions with an amide and/or ester...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/72 (2006.01) A61K 9/14 (2006.01) A61K 47/18 (2006.01)

Patent

CA 2470498

The invention comprises a medicinal aerosol composition comprising a propellant, an excipient comprising an acid or amine end-group and at least one and no more than two amide and/or ester functional groups, and a drug. The invention also comprises particulate medicinal compositions comprising particles with a mean mass aerodynamic diameter of less than about 10 microns that incorporate an excipient containing an acid or amine end-group and at least one and no more than two amide and/or ester functional groups.

L'invention concerne une composition médicinale en aérosol qui contient un propulseur, un excipient comportant un groupe terminal acide ou amine et au moins un ou au plus deux groupes à fonction amide et/ou ester, ainsi qu'un médicament. Par ailleurs, l'invention concerne des compositions médicinales particulaires dont les particules présentent un diamètre aérodynamique de masse inférieur à environ 10 microns et renferment un excipient qui comporte un groupe terminal acide ou amine et au moins un et au plus deux groupes à fonction amide et/ou ester.

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