Medicinal aerosol formulations comprising budesonide

A - Human Necessities – 61 – K

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A61K 9/72 (2006.01) A61K 9/10 (2006.01) A61K 31/58 (2006.01)

Patent

CA 2266431

A pharmaceutical aerosol formulation, suitable for administration by oral or nasal inhalation, containing a suspension of particulate budesonide, hydrofluoroalkane propellant and, optionally, additional hydrofluoroalkane propellants, surfactant selected from oleic acid, sorbitant oleates and lecithin, and adjuvant have a Kauri-butanol value of at least 10.

Formulation pour aérosol pharmaceutique, adaptée à l'administration par voie orale ou par inhalation nasale, contenant une suspension de budesonide particulaire, un agent propulseur hydrofluoroalcane et éventuellement des agents propulseurs hydrofluoroalcane additionnels, un tensioactif sélectionné parmi l'acide oléique, les oléates de sorbitanne et la lécithine, ainsi qu'un adjuvant, et possédant un indice de kauri-butanol d'au moins 10.

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