Medicinal association of a biguanide (metformin) and a...

C - Chemistry – Metallurgy – 07 – C

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C07C 251/08 (2006.01) A61K 31/132 (2006.01) A61K 31/155 (2006.01) A61K 31/198 (2006.01) A61K 47/48 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2435484

The invention concerns a medicinal combination, for treating diabetes, in particular type 2 diabetes, associating a biguanine, in particular a N-dimethylbiguanine, as first medicine, and a carrier agent for said biguanine, as second medicine, said combination comprising: a) a therapeutically active amount of biguanine; b) and an amount of the carrier agent, predetermined to potentiate the therapeutic activity of the biguanine as per (a).

Ensemble médicamenteux, pour le traitement du diabète, en particulier du diabète de type 2, associant une biguanine, en particulier une N- diméthylbiguanine, en tant que premier médicament, et un agent transporteur de ladite biguanine, en tant que second médicament, le dit ensemble comprenant: e) une quantité thérapeutiquement active de la biguanine f) et une quantité de l'agent transporteur, prédeterminée pour potentialiser l'activité thérapeutique de la biguanine selon (a).

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