Medicinal composition

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/20 (2006.01) A61K 9/00 (2006.01) A61K 31/38 (2006.01) A61K 31/4704 (2006.01) A61K 31/4709 (2006.01) A61K 45/08 (2006.01) A61K 47/12 (2006.01) A61K 47/18 (2006.01) A61P 1/04 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2449952

The present invention provides a medicinal composition comprising (1) a pharmacologically active substance, (2) a drug absorbefacient and (3) a taurine compound or a polyamine. A taurine compound has an efect of suppressing or preventing damage of the intestinal mucous membrane, and therefore adding the taurine compound to a medicinal composition containing a pharmacologically active substance and a drug absorbefacient makes it possible to suppress or prevent damage of the intestinal mucosa. A polyamine improves the absorbability of pharmacologically active substances, and therefore adding the polyamine to a medicinal composition containing a pharmacologically active substance and a drug absorbefacient makes it possible to decrease the dose of the drug absorbefacient, thereby suppressing or preventing damage of the intestinal mucosa.

L'invention concerne des compositions médicinales contenant? ¿(1) une substance active au niveau pharmacologique, (2) une substance absorbefaciente et (3) un composé de taurine ou une polyamine. Le composé de taurine permet de diminuer ou d'empêcher les blessures de la muqueuse intestinale. Grâce à l'ajout du composé de taurine à des compositions médicinales contenant une substance active au niveau pharmacologique et une substance absorbefaciente, les blessures de la muqueuse intestinale dues à la substance absorbefaciente peuvent être diminuées ou empêchées. La polyamine améliore la capacité d'absorption d'une substance active au niveau pharmacologique. Grâce à l'ajout de polyamine à des compositions médicinales contenant une substance active au niveau pharmacologique et une substance absorbefaciente, la dose de substance absorbefaciente peut être diminuée et par conséquent les blessures de la muqueuse intestinale peuvent être diminuées ou empêchées.

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