A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/50 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2561436
The present invention relates to a medicinal composition for preventing or treating pancreatic cancer, comprising 3-alkoxy-6-allylthiopyridazine or a pharmaceutically acceptable salt thereof as an effective ingredient. An MTT assay, to assess the viability of cells, and flow cytometric analysis, to measure apoptotic cell death, were performed, and the results, which revealed that the compound and pharmaceutically acceptable salts thereof have preventive and therapeutic activity against pancreatic cancer, are presented herein.
La présente invention concerne une composition médicinale destinée à prévenir ou traiter le cancer du pancréas. La composition comprend de la 3-alcoxy-6-allylthiopyridazine ou l'un de ses sels pharmaceutiquement acceptables en tant qu'agent actif. L'invention divulgue les résultats d'un dosage colorimétrique MTT, visant à évaluer la viabilité des cellules, et d'une analyse cytométrique de flux, visant à mesurer la mort des cellules apoptotiques, lesquels ont démontré l'activité préventive et thérapeutique du composé et de ses sels pharmaceutiquement acceptables sur le cancer du pancréas.
Kwon Soon-Kyoung
Lee Yong-Soo
Park Hae-Sun
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Kwon Soon-Kyoung
Seoul Pharm. Co. Ltd.
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