Medicinal composition for improving angiotension-regulating...

C - Chemistry – Metallurgy – 07 – D

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C07D 307/79 (2006.01) A61K 31/343 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) C07D 307/78 (2006.01)

Patent

CA 2482703

A novel medicinal composition for improving the angiotension-regulating function of the blood vessel endothelium which contains a compound represented by the formula (1): (1) wherein R1 is hydrogen, acyl, or arylalkyloxycarbonyl; and R2 and R3 may be the same or different and each is optionally substituted alkyl, optionally substituted alkenyl, or optionally substituted alkynyl, provided that R2 and R3 may be bonded to each other to form cycloalkyl.

Cette invention concerne une composition médicinale permettant d'améliorer la fonction de régulation de l'angiotensine de l'endothélium de vaisseau sanguin et contenant un composé représenté par la formule (1) dans laquelle R¿1? désigne hydrogène, acyle ou arylalkyloxycarbonyle ; et R¿2? et R¿3? peuvent être identiques ou différents et désignent chacun alkyle éventuellement substitué, alcényle éventuellement substitué ou alcynyle éventuellement substitué sous réserve que R¿2? et R¿3 ?soient liés l'un à l'autre pour former cycloalkyle.

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