Medicinal compositions for opthalmic use

Details Medicinal compositions for opthalmic use Medicinal compositions for opthalmic use

A - Human Necessities

61

K

A61K 45/00 (2006.01) A61K 31/4045 (2006.01) A61P 27/02 (2006.01) A61P 27/06 (2006.01) C07D 209/12 (2006.01) C07D 209/42 (2006.01)

Patent

CA 2453476

Excellent medicinal compositions for treating or preventing glaucoma or diseases in association with ocular hypertension which can be continuously used over a long time while preventing the occurrence of drug-tolerance caused by continuous administration. Medicinal compositions such as eyedrops characterized by containing as the active ingredient a neutral antagonist to .alpha.1A-AR.

Cette invention se rapporte à des compositions de médicaments ayant d'excellentes propriétés, qui servent à traiter ou à prévenir les glaucomes ou les maladies associées à une hypertension oculaire et qui peuvent être utilisées en continu sur une longue période, tout en empêchant l'apparition de la tolérance au médicament causée par une administration continue. De telles compositions de médicaments, par exemple sous la forme de gouttes ophtalmologiques, se caractérisent en ce qu'elles contiennent comme principe actif un antagoniste neutre contre .alpha.¿1A?-AR.

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