Medicinal formula of theophylline having a lasting action

A - Human Necessities – 61 – K

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A61K 31/52 (2006.01) A61K 31/165 (2006.01) A61K 31/415 (2006.01) C07D 263/04 (2006.01)

Patent

CA 1199582

ABREGE DESCRIPTIF L'invention concerne des formes de théophylline à action prolongée. La théophylline, sous forme libre ou de sel est associée à un composé du type cinnamamide substitué répondant à la formule générale Image (I) dans laquelle R est l'hydrogène, un halogène ou un radical acétyle; R1 est l'hydrogène ou le radical méthyle; R2 représente un groupe de formule (II) dans Image laquelle R3 est l'hydrogène ou le radical méthyle, R1 et R2 peuvent également former avec l'atome d'azote adjacent le groupe diméthyl-2,2 oxazolidinyl-3. Médicament utilisable dans le traitement de l'asthme.

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