Medicinal inhalation devices and components thereof

Details Medicinal inhalation devices and components thereof Medicinal inhalation devices and components thereof

B - Operations, Transporting

05

D

B05D 5/08 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2760808

A composition for modifying a surface of a substrate, the composition comprising: (a) a first polyfluoropolyether silane of the Formula Ia: CF3CF2CF2O(CF(CF3)CF2O)pCF(CF3)-C(O)NH(CH2)3Si(Y)3 wherein each Y is independently a hydrolyzable group and wherein p is 3 to 50; and (b) a second polyfluoropolyether silane of the Formula IIa: (Y')3Si(CH2)3NHC(O)-CF2O(CF2O)m(C2F4O)qCF2-C(O)NH(CH2)3Si(Y')3 wherein each Y' is independently a hydrolyzable group and wherein m is 1 to 50 and q is 3 to 40. A method of making a medicinal inhalation device or a component of a medicinal inhalation device comprising a step of applying to at least a portion of a surface of the device or the component, respectively, the composition.

La présente invention se rapporte à une composition destinée à modifier une surface d'un substrat, la composition comprenant : (a) un premier silane de polyfluoropolyéther de la formule Ia: CF3CF2CF2O(CF(CF3)CF2O)pCF(CF3)-C(O)NH(CH2)3Si(Y)3, chaque Y étant indépendamment un groupe hydrolysable et p étant compris entre 3 et 50 ; et (b) un second silane de polyfluoropolyéther de la formule IIa: (Y')3Si(CH2)3NHC(O)-CF2O(CF2O)m(C2F4O)qCF2-C(O)NH(CH2)3Si(Y')3, chaque Y' étant indépendamment un groupe hydrolysable et m étant compris entre 1 et 50 et q étant compris entre 3 et 40. L'invention se rapporte également à un procédé de fabrication d'un dispositif d'inhalation de médicaments ou à un composant d'un dispositif d'inhalation de médicaments comprenant une étape consistant à appliquer la composition sur au moins une partie d'une surface du dispositif ou du composant, respectivement.

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