A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/15 (2006.01) A61K 38/12 (2006.01) A61P 13/08 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/34 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2457043
Remedies for prostatic cancer and malignant lymphoma comprising FK228 or its salt as the active ingredient; and a method of evaluating the antitumor effect of a histone deacetylase inhibitor characterized by comprising at least the step of treating test cells with the histone deacetylase inhibitor and the step of measuring a change in the expression of a specific gene in the test cells before and after the treatment with the inhibitor and comparing the expression doses thus measured.
L'invention concerne des compositions thérapeutiques destinées au cancer de la prostate et au lymphome malin et comprenant un inhibiteur FK228 ou son sel comme ingrédient actif. L'invention concerne également une méthode d'évaluation de l'activité antitumorale d'un inhibiteur d'histone désacétylase. Cette méthode se caractérise en ce qu'elle consiste au moins à traiter des cellules tests avec cet inhibiteur d'histone désacétylase, à mesurer un changement d'expression d'un gène spécifique dans les cellules tests avant et après ce traitement, puis à comparer les doses d'expression ainsi mesurées.
Naoe Yoshinori
Sasakawa Yuka
Astellas Pharma Inc.
Fujisawa Pharmaceutical Co. Ltd.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
LandOfFree
Medicinal use of histone deacetylase inhibitor and method of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Medicinal use of histone deacetylase inhibitor and method of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Medicinal use of histone deacetylase inhibitor and method of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1433925