C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/02 (2006.01) A61K 31/7048 (2006.01)
Patent
CA 2665603
The use of macrolide polyene antibiotics or derivatives or analogues thereof as culture supplement for the propagation of virus is described. Further pharmaceutical compositions comprising a virus and a macrolide polyene antibiotic or a derivative or analogue thereof and methods for using of macrolide polyene antibiotics for transfection and infection of cells as well as the use of macrolide poylene antibiotics for the isolation of virus from clinical samples are disclosed.
La présente invention concerne l'utilisation d'antibiotiques macrolides polyènes ou de leurs dérivés ou analogues en tant que complément de culture pour la propagation de virus. L'invention concerne en outre des compositions pharmaceutiques comprenant un virus et un antibiotique macrolide polyène ou son dérivé ou analogue, ainsi que des procédés d'utilisation des antibiotiques macrolides polyènes pour la transfection et l'infection de cellules de même que des procédés d'utilisation des antibiotiques macrolides polyènes pour l'isolement de virus dans des échantillons cliniques.
Egorov Andrej
Roethl Elisabeth
Avir Green Hills Biotechnology Research Development Trade Ag
Sim & Mcburney
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