Megakaryocyte and platelet growth, production and composition

Details Megakaryocyte and platelet growth, production and composition Megakaryocyte and platelet growth, production and composition

C - Chemistry, Metallurgy

12

N

C12N 5/08 (2006.01) C07K 14/475 (2006.01) C12N 5/02 (2006.01) C12N 5/06 (2006.01) C12Q 1/06 (2006.01) C12Q 1/48 (2006.01)

Patent

CA 2069879

2069879 9206178 PCTABS00011 Megakaryocytes and platelets are produced in culture by employing conditions encouraging megakaryopoiesis while discouraging the formation of fibroblasts. Particularly, human plasma or heparin with fetal calf serum is found to support megakaryocyte formation in containers which lack fibroblast supporting coatings. A factor associated with megakaryopoiesis is provided.

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