Megakaryocyte differentiation factor

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/18 (2006.01) A01K 67/04 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 14/475 (2006.01) C07K 14/52 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12N 15/19 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2100690

A novel megakaryocyte differentiation factor, for example, consisting essentially of SEQ ID NO: 30; DNA coding for the megakaryocyte differentiation factor, an expression vector comprising the DNA, a host transformed with the expression vector, and a process for production of the megakaryocyte differentiation factor using the host. The megakaryocyte differentiation factor accelerates differentiation of megakaryocytes in the presence of IL-3, and acts as a thrombopoietin, and therefore an effective medicament to various diseases involving a decrease in platelets.

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