Megakaryocyte production

Details Megakaryocyte production Megakaryocyte production

A - Human Necessities

61

K

167/103.2

A61K 38/19 (2006.01) A61K 38/20 (2006.01)

Patent

CA 2031233

MEGAKARYOCYTE PRODUCTION Abstract of the Disclosure A method of increasing megakaryocyte production is disclosed. Such method comprises administering to a mammal a pharmaceutically effective amount of G-CSF and a pharmaceutically effective amount of IL-3 or GM-CSF, and optionally a pharmaceutically effective amount of IL-6. Another method comprises administering GM-CSF and IL-5. Also disclosed are compositions for use in increasing megakaryocyte production. A method of increasing blood platelet production is also disclosed. Such method comprises administering to a mammal a pharmaceutically effective amount of IL-6 and optionally a pharmaceutically effective amount of IL-3, G-CSF or GM-CSF. Also disclosed are compositions for use in increasing blood platelet production. A-181

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