C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 19/00 (2006.01) A61K 38/00 (2006.01) A61K 38/16 (2006.01) A61K 48/00 (2006.01) C07K 7/00 (2006.01) C07K 14/00 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C12N 9/12 (2006.01) C12N 15/11 (2006.01) C12N 15/62 (2006.01) C12N 15/66 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2680837
The invention relates to kinase ligands and polyligands. In particular, the invention relates to ligands, homopolyligands, and heteropolyligands that modulate MEK activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands, homopolyligands, and heteropolyligands to a cellular localization signal, epitope tag and/or a reporter. The invention also includes polynucleotides encoding the ligands and polyligands.
La présente invention concerne des ligands et des polyligands de kinase. En particulier, l'invention concerne des ligands, des homopolyligands, et des hétéropolyligands qui modulent l'activité de la MEK. Les ligands et les polyligands sont utilisés comme outils de recherche ou comme agents thérapeutiques. L'invention comprend la liaison des ligands, des homopolyligands, et des hétéropolyligands à un signal de localisation cellulaire, un marqueur d'épitope et/ou un rapporteur. L'invention comprend également des polynucléotides codant pour les ligands et les polyligands.
Atzel Amy
Bachinsky David
Carson Jonathan
Reed Thomas
Borden Ladner Gervais Llp
Intrexon Corporation
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