Melanin concentrating hormone receptor antagonists

Details Melanin concentrating hormone receptor antagonists Melanin concentrating hormone receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 207/06 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2534428

Novel compounds, or pharmaceutically-acceptable salts, tautomers or prodrugs thereof, of Formula (I) (I) wherein W, X, Y, Z, R3-R6 , and R11 are as defined in the specification, are provided. Also provided are methods of treating or preventing a melanin concentrating hormone-mediated disorder in a subject, comprising administering to a subject in need of such treatment or prevention a compound of Formula I.

L'invention concerne des nouveaux composés ou des sels, des tautomères ou des promédicaments de ceux-ci acceptables sur le plan pharmaceutique de formule générale (I) dans laquelle W, X, Y, Z, R?3¿-R?6¿ et R?11¿ ont la signification indiquée dans la description. L'invention concerne également des méthodes de traitement ou de prévention d'un trouble dont la médiation est assurée par l'hormone concentrant la mélanine chez un sujet, qui consistent à administrer à un sujet nécessitant un tel traitement ou une telle prévention un composé de formule (I).

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