Melanin formation-inhibitory protein, and its preparation...

Details Melanin formation-inhibitory protein, and its preparation... Melanin formation-inhibitory protein, and its preparation...

C - Chemistry, Metallurgy

12

P

C12P 21/00 (2006.01) A61K 8/64 (2006.01) A61K 8/98 (2006.01) A61K 38/17 (2006.01) A61Q 19/02 (2006.01) C07K 14/47 (2006.01) A61K 7/02 (1990.01)

Patent

CA 2104043

Abstract of the Disclosure A novel melanin formation-inhibitory protein, which has a molecular weight of 90,000?20,000 and a pI of 5.5?0.5, exerts a tyrosinase formation-inhibitory activity in pigment cells but does not substantially inhibit the inherent tyrosinase activity. Thus the protein is advantageously used as a pharmaceutical and cosmetic in the prevention and/or treatment for local chromatosises such as chloasma, ephelis and sunburn, as well as systemic chromatosises such as addisonism.

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