C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/06 (2006.01) C07D 233/20 (2006.01) C07D 233/22 (2006.01) C07D 233/42 (2006.01) C07D 233/48 (2006.01) C07D 235/18 (2006.01) C07D 401/04 (2006.01) C07D 403/10 (2006.01) C07D 405/10 (2006.01) C07D 405/14 (2006.01) C07D 409/04 (2006.01) C07D 409/10 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 513/04 (2006.01)
Patent
CA 2529445
Provided are MC4-R binding compounds of the formula XVII: (XVII), wherein L2 is a linker group, and P1, P2, P3, P4, Z1, Z2, Z3, Z4, Z5, t, s, and R are as described in the specification. Methods of using the compounds to treat MC4-R associated disorders, such as disorders associated with weight loss, are also provided.
La présente invention a trait à des composés de liaison de MC4-R de formule XVII, dans laquelle: L¿2? est un groupe lieur, et P?1¿, P?2¿, P?3¿, P?4¿, Z?1¿, Z?2¿, Z?3¿, Z?4¿, Z?5¿, t, s, et R sont tels que définis dans la description. L'invention a également trait à des composés pour le traitement de troubles associés au MC4-R, tels que des troubles associés à la perte de poids.
Claiborne Christopher F.
Dai Mingshi
Maguire Martin
Marsilje Thomas H.
Patane Michael
Gene Logic Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Ore Pharmaceuticals Inc.
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