Melanocortin metallopeptide constructs, combinatorial...

C - Chemistry – Metallurgy – 07 – K

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C07K 5/00 (2006.01) A61K 38/00 (2006.01) C07K 1/00 (2006.01) C07K 1/04 (2006.01) C07K 2/00 (2006.01) C07K 5/10 (2006.01) C07K 14/655 (2006.01) C07K 14/665 (2006.01)

Patent

CA 2379647

Metallopeptides and metallopeptide combinatorial libraries specific for melanocortin receptors are provided, for use in biological, pharmaceutical and related applications. The metallopeptides and combinatorial libraries are made of peptides, peptidomimetics and peptide-like constructs, in which the peptide, peptidomimetic or construct is conformationally fixed on complexation of a metal ion-binding portion thereof with a metal ion.

Cette invention concerne des métallopeptides et des banques combinatoires de métallopeptides spécifiques des récepteurs de la mélanocortine qui conviennent pour des applications biologiques, pharmaceutiques et autres applications connexes. Les métallopeptides et les banques combinatoires sont constitués de peptides, de peptidomimétiques et constructions de type peptide dans lesquels le peptide, le peptidomimétique ou la construction est fixé du point de vue de la conformation au moment de la mise en complexe d'une partie de liaison d'ions métal avec un ion métal.

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