Melanocortin type 4 receptor agonist piperidinoylpyrrolidines

C - Chemistry – Metallurgy – 07 – D

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C07D 401/14 (2006.01)

Patent

CA 2642922

The present invention relates to a class of melanocortin MCR4 agonists of general formula (I), wherein the variables and substituents are as defined herein and especially to selective MCR4 agonist compounds, to their use in medicine, particularly in the treatment of sexual dysfunction and obesity, to intermediates useful in their synthesis and to compositions containing them.

La présente invention concerne une classe d'agonistes du MCR4 de formule générale (I), les variables et substituants étant tels que définis dans la présente invention, et plus spécialement des composés agonistes de MCR4 sélectifs, leurs applications en médecine, en particulier dans le traitement des dysfonctionnements sexuels et de l'obésité, des intermédiaires pouvant être employés dans leur synthèse et des compositions les incluant.

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