Melatonergic agents

Details Melatonergic agents Melatonergic agents

C - Chemistry, Metallurgy

07

C

C07C 233/17 (2006.01) A61K 31/16 (2006.01) A61K 31/195 (2006.01) C07C 233/18 (2006.01) C07C 233/20 (2006.01) C07C 233/60 (2006.01) C07C 235/08 (2006.01) C07C 235/80 (2006.01) C07C 275/24 (2006.01)

Patent

CA 2159759

New melatonergic agents are phenyl alkanyl or phenyl alkyl substituted carboxamides and ureas of Formula I: Image wherein: R1 = C1-3 alkyl, allyl, C3-6 cycloalkyl substituted C1-4 alkyl; R2 = hydrogen, halogen or C1-4 alkoxy; R3 = hydrogen or C1-4 alkyl; R4 = C1-4 alkyl, C1-4 alkyl substituted amino, carboxylic acid substituted C1-4 alkyl or C3-6 cycloalkyl, C1-4 alkoxy substituted C1-4 alkyl, C3-6 cycloalkyl, or straight or branched chain C2-4 alkenyl; A = a linear C2-4 alkanediyl or alkenediyl chain, provided that A not be CH2CH2- when X is a bond; and X = a covalent bond or oxygen.

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