Melatonin derivatives and medicine containing same

Details Melatonin derivatives and medicine containing same Melatonin derivatives and medicine containing same

C - Chemistry, Metallurgy

07

D

C07D 209/16 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2355704

The invention concerns melatonin derivatives of formula (I) wherein: R¿1? represents H, a C¿1?-C¿4? alkyl group or a C¿1?-C¿4? alkoxy group; R¿2? represents H or a C¿1?-C¿4? alkyl group; R¿3? represents H, methyl or a halogen atom; R¿4?, R¿5? represent individually H or a halogen atom; R¿6? represents H or a C¿1?-C¿4? alkyl group, or a pharmaceutically acceptable salt thereof. The invention also concerns a medicine comprising said derivatives.

L'invention concerne des dérivés de mélatonine de formule (I) dans laquelle: R1 représente H, un groupe alkyle en C1 à C4 ou un groupe alcoxy en C1 à C4. R2 représente H ou un groupe alkyle en C1 à C4, R3 représente H, méthyle ou un atome d'halogène, R4, R5 représentent individuellement H ou un atome d'halogène, R6 représente H ou un groupe alkyle en C1-C4 ou un sel pharmaceutiquement acceptable de celui-ci. Elle concerne également un médicament comprenant de tels dérivés.

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