Melks as modifiers of the rac pathway and methods of use

Details Melks as modifiers of the rac pathway and methods of use Melks as modifiers of the rac pathway and methods of use

G - Physics

01

N

G01N 33/53 (2006.01)

Patent

CA 2535808

Human MELK genes are identified as modulators of the RAC pathway, and thus are therapeutic targets for disorders associated with defective RAC function. Methods for identifying modulators of RAC, comprising screening for agents that modulate the activity of MELK are provided.

Les gènes MELK humains sont identifiés comme étant des modulateurs du mécanisme d'action de RAC. Par conséquent, ils servent de cibles thérapeutiques pour soigner les troubles associés à un dysfonctionnement de RAC. Par ailleurs, l'invention concerne des procédés d'identification des modulateurs de RAC, qui consistent à cribler des agents modulant l'activité de MELK.

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