Melphalan derivatives and their use as cancer...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 5/06 (2006.01) A61K 38/05 (2006.01) A61P 35/00 (2006.01) C07K 5/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2408501

The invention refers to new alkylating di- and tripeptides based on a melphalan unit, and one or two additional amino acids or amino acid derivatives, which can be used in the treatment of carcinogenic diseases. Further, the invention refers to a pharmaceutical composition comprising the alkylating peptides of the invention.

L'invention concerne de nouveaux dipeptides et tripeptides d'alkylation basés sur une unité de melphalan et un ou deux acide(s) aminé(s) ou dérivé(s) d'acide(s) aminé(s) additionnels et pouvant être utilisés pour traiter les maladies cancéreuses. L'invention concerne également une composition pharmaceutique comprenant les peptides d'alkylation de l'invention.

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