Melt extruded controlled release oxycodone multiparticulates

Details Melt extruded controlled release oxycodone multiparticulates Melt extruded controlled release oxycodone multiparticulates

A - Human Necessities

61

K

A61K 31/485 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2530385

Multipartulates of oxycodone can be made by extrusion of a blend which suitably contains (a) oxycodone, (b) water-insoluble ammonium methacrylate copolymer, (c) plasticiser, (d) lubricant and (e) water permeability modifier.

L'invention concerne des substances multiparticulaires d'oxycodone pouvant être obtenues par extrusion d'un mélange qui contient (a) un oxycodone, (b) un copolymère méthacrylate d'ammonium insoluble dans l'eau, (c) un plastifiant, (d) un lubrifiant et (e) un modificateur perméable à l'eau.

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