Membrane invasion culture system

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/04 (2006.01) C12M 3/00 (2006.01) G01N 15/00 (2006.01)

Patent

CA 1266603

MEMBRANE INVASION CULTURE SYSTEM ABSTRACT OF THE DISCLOSURE A cell culture system for performing cell invasion assays comprises a base plate and a top plate. The base plate includes a plurality of wells formed in one face thereof, while the top plate includes a plurality of apertures arranged in substantially the same pattern as the wells in the base plate. By placing a test membrane between the plates and securing them together, a plurality of test receptacles are formed, each receptacle having an upper chamber and a lower chamber separated by the test membrane. Invasion assays are performed by filling the lower chamber with a suitable culture medium and seeding the cells to be tested in the upper chamber.

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