Membrane method for the determination of an organic acid

G - Physics – 01 – N

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G01N 30/00 (2006.01) G01N 33/18 (2006.01)

Patent

CA 2101749

2101749 9215012 PCTABS00015 A chemical analysis method for the determination of a first organic acid in the presence of a second organic acid both of which are in a solution to be analyzed. The first step is to form a pH adjusted solution to be analyzed such that the first acid is predominately in its unionized form and so that the second acid is predominately in its ionized form. The second step is to partition the pH adjusted solution to be analyzed from a receiving solution with a semipermeable membrane. The last step is to determine the concentration of the first acid in the receiving solution so that the concentration of the first acid in the solution to be analyzed can be estimated. Valve (15) is actuated and a predetermined volume of solution to be analyzed is added to the flowing stream of liquid buffer adjusting its pH to that of the buffer and is carried to the inside of the membrane (22). The first acid permeates into the membrane (22) from the pH adjusted solution and then out of the membrane (22) into the flowing receiving solution and is conducted to the detector (25).

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