Membrane penetrating peptides and uses thereof

C - Chemistry – Metallurgy – 12 – N

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C12N 15/00 (2006.01) C07K 14/47 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2420350

The present invention is directed to membrane penetrating peptides useful as in vivo, ex vivo and in vitro intracellular delivery devices for compound of interest. More particularly, the invention involves identification of membrane penetrating peptides which may be used as protein carriers for delivery of acompound of interest to cells, to methods of delivering a compound of interest attached to membrane penetrating peptides to cells.

L'invention concerne des peptides de pénétration de membrane, utiles en tant que dispositifs d'apport intracellulaire <i>in vivo</i>, <i>ex vivo</i> et <i>in vitro</i> d'un composé présentant un intérêt. L'invention concerne notamment l'identification de peptides de pénétration de membrane, utiles en tant que supports protéiques servant à apporter aux cellules un composé présentant un intérêt, ainsi que des procédés d'apport d'un tel composé attaché aux peptides de pénétration de la membrane cellulaire.

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