Membrane-permeant peptide complexes for medical imaging,...

Details Membrane-permeant peptide complexes for medical imaging,... Membrane-permeant peptide complexes for medical imaging,...

A - Human Necessities

61

K

A61K 51/08 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2407399

Methods and compositions for medical imaging, evaluating intracellular processes and components, radiotherapy of intracellular targets, and drug delivery by the use of novel cell membrane-permeant peptide conjugate coordination and covalent complexes having target cell specificity are provided. Kits for conjugating radionuclides and other metals to peptide coordination complexes are also provided.

L'invention concerne des procédés et des compositions s'utilisant en imagerie médicale, pour évaluer des processus et des composés intracellulaires, la radiothérapie de cibles intracellulaires, et l'administration de médicaments par utilisation de nouveaux complexes covalents et de coordination conjugués de peptides perméables aux membranes cellulaires, lesdits complexes covalents ayant une spécificité de cellules cibles. L'invention concerne également des coffrets pour conjuguer des radionucléïdes et d'autres métaux à des complexes de coordination de peptides.

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