Membrane-permeant peptide complexes for medical imaging,...

Details Membrane-permeant peptide complexes for medical imaging,... Membrane-permeant peptide complexes for medical imaging,...

A - Human Necessities

61

K

A61K 51/00 (2006.01) A61M 36/14 (2006.01)

Patent

CA 2516282

Methods and compositions for medical imaging, evaluating intracellular processes and components, radiotherapy of intracellular targets, and drug delivery by the use of novel cell membrane-permeant peptide conjugate coordination and covalent complexes having target cell specificity are provided. Kits for conjugating radionuclides and other metals to peptide coordination complexes are also provided.

L'invention concerne des méthodes et des compositions utilisées dans l'imagerie médicale, l'évaluation de processus et de composants intracellulaires, la radiothérapie de cibles intracellulaires et l'administration de médicaments à l'aide de nouveaux complexes covalents de coordination de conjugués peptidiques de perméation membranaire présentant une spécificité de cellules cibles. L'invention concerne également des trousses permettant de conjuguer des radionucléides et d'autres métaux avec des complexes peptidiques de coordination.

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