Men1 is a marker and therapeutic target for breast and...

Details Men1 is a marker and therapeutic target for breast and... Men1 is a marker and therapeutic target for breast and...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 31/7088 (2006.01) A61K 31/713 (2006.01) A61P 35/00 (2006.01) C12Q 1/02 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2656824

The present invention provides genomic markers for determining the presence or absence of breast cancer. The invention further demonstrates that inhibition of MEN1 reduces breast or prostate cancer proliferation, thereby demonstrating that inhibition of MEN1 activity or expression can be used to reduce breast cancer or prostate cancer proliferation in an individual in need thereof.

La présente invention propose des marqueurs génomiques pour déterminer la présence ou l'absence d'un cancer du sein. L'invention démontre en outre que l'inhibition de MEN1 réduit la prolifération du cancer du sein ou de la prostate, ce qui démontre ainsi que l'on peut utiliser l'inhibition de l'activité de MEN1 ou de son expression pour réduire la prolifération du cancer du sein ou de la prostate chez un individu demandeur.

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