Meningococcal vaccines including hemoglobin receptor

Details Meningococcal vaccines including hemoglobin receptor Meningococcal vaccines including hemoglobin receptor

A - Human Necessities

61

K

A61K 39/095 (2006.01) C07K 19/00 (2006.01) C12N 1/20 (2006.01)

Patent

CA 2747340

The meningococcal haemoglobin receptor, HmbR, is used as a vaccine antigen in combination with one or more further antigens e.g. in combination with a meningococcal outer membrane vesicle, with another purified meningococcal antigen (e.g. fHBP, 287, NadA, NspA, NhhA, App, Omp85, LOS), with a conjugated meningococcal capsular saccharide, etc.

Selon l'invention, le récepteur de l'hémoglobine méningococcique, HmbR, est utilisé en tant qu'antigène vaccinal combiné avec un ou plusieurs autres antigènes, par exemple combiné à une vésicule membranaire externe méningococcique, à un autre antigène méningococcique purifié (par exemple, fHBP, 287, NadA, NspA, NhhA, App, Omp85, LOS), à un saccharide capsulaire méningococcique conjugué etc.

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