Mercapto acyl-carnitines, process for their preparation and...

C - Chemistry – Metallurgy – 07 – C

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260/492.1

C07C 323/52 (2006.01) A61K 31/095 (2006.01) A61K 31/195 (2006.01) A61K 31/205 (2006.01) A61K 31/21 (2006.01) A61K 31/22 (2006.01) A61K 31/23 (2006.01) A61K 31/24 (2006.01) A61K 31/255 (2006.01) A61K 31/265 (2006.01)

Patent

CA 1168259

"Mercapto acyl-carnitines, process for their preparation and pharmaceutical compositions containing same". Abstracts of the disclosures A novel class of mercapto acyl-carnitines is disclosed, wherein the mercapto acyl radical is the radical of saturat- ed mercapto acids having from 2 to 10 carbon atoms. These mercapto acyl-carnitines are prepared e.g. by first preparing the corresponding halogen acyl-carnitine and then substitut- ing therein, by nucleophylic substitution, the -SH group for the halogen atom. These mercapto acyl-carnitines are useful therapeutic agents, e.g. for the treatment of intoxications and burns and as mucolytic agents.

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