Mercapto derivatives as inhibitors of cyclooxygenases

Details Mercapto derivatives as inhibitors of cyclooxygenases Mercapto derivatives as inhibitors of cyclooxygenases

A - Human Necessities

61

K

A61K 31/155 (2006.01) A61K 31/395 (2006.01)

Patent

CA 2247121

This invention is directed to a pharmacologically acceptable composition for inhibiting cyclooxygenase in a mammal, which includes a mercapto derivative and a pharmaceutically acceptable carrier. The invention also concerns a method of inhibiting cyclooxygenase and treating various conditions where there is an advantage in inhibiting prostaglandins biosynthesis. The method includes the step of administering to a mammal a mercapto derivative in pure form or in a pharmaceutically acceptable carrier.

Cette invention concerne une composition acceptable sur le plan pharmacologique, laquelle composition permet d'inhiber la cyclo-oxygénase chez les mammifères et comprend un dérivé mercapto ainsi qu'un véhicule acceptable sur le plan pharmaceutique. Cette invention concerne également un procédé d'inhibition de cyclo-oxygénase et de traitement de divers états où l'on a intérêt a inhiber la biosynthèse de prostaglandine. Ce procédé consiste à administrer à un mammifère un dérivé mercapto sous sa forme pure ou dans un véhicule acceptable sur le plan pharmaceutique.

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