Mesalazine controlled release oral pharmaceutical compositions

Details Mesalazine controlled release oral pharmaceutical compositions Mesalazine controlled release oral pharmaceutical compositions

A - Human Necessities

61

K

A61K 31/606 (2006.01) A61K 9/22 (2006.01) A61K 9/52 (2006.01)

Patent

CA 2377299

Controlled-release oral pharmaceutical compositions containing as active ingredient 5-amino-salicylic acid, com-prising: a) an inner lipophilic matrix consisting of substances with melting point below 90 °C in which the active ingredient is at least partly inglobated; b) an outer hydrophilic matrix in which the lipophilic matrix is dispersed; c) optionally other excipients.

La présente invention concerne des compositions pharmaceutiques orales à libération régulée contenant de l'acide 5-amino-salicyclique en tant que substance active et comprenant : a) une matrice lipophile interne composée de substances dont le point de fusion est inférieur à 90 DEG C et dans laquelle la substance active est au moins partiellement englobée; b) une matrice hydrophile externe dans laquelle la matrice lipophile est dispersée; c) éventuellement d'autres excipients.

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