Metabolic gene polynucleotides and polypeptides and uses...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 31/713 (2006.01) A61K 38/17 (2006.01) A61P 3/00 (2006.01) C07K 14/47 (2006.01) C12N 5/10 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2433449

The present invention relates to the field of metabolic research. Metabolic disorders, such as obesity, are a public health problem that is serious and widespread. GMG-3, GMG-4, Cluster 1, GMG-6A, or GMG-6B polypeptides have been identified that are beneficial in the treatment of metabolic disorders. These compounds should be effective for reducing body mass and for treating metabolic-related diseases and disorders. These metabolic-related diseases and disorders include hyperlipidemias, atherosclerosis, diabetes, and hypertension.

La présente invention concerne le domaine de la recherche métabolique. Des troubles métaboliques tels que l'obésité constituent un problème de santé publique grave et étendu. Des polypeptides de GMG-3, GMG-4, Groupe 1, GMG-6A ou GMG-6B ont été identifiés, lesquels sont bénéfiques dans le traitement de troubles métaboliques. Ces composés devraient être efficaces pour réduire la masse corporelle et pour traiter des maladies et des troubles d'ordre métabolique. Ces maladies et troubles d'ordre métabolique comprennent des hyperlipidémies, l'athérosclérose, le diabète et l'hypertension.

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