Metabolic intervention with glp-1 or its biologically active...

A - Human Necessities – 61 – K

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A61K 38/26 (2006.01) A61K 31/7004 (2006.01) A61K 33/00 (2006.01) A61K 38/06 (2006.01) A61K 38/44 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2368772

It has now been discovered that GLP-1 treatment after acute stroke or hemorrhage, preferably intravenous administration, can be an ideal treatment because it provides a means for optimizing insulin secretion, increasing brain anabolism, enhancing insulin effectiveness by suppressing glucagon, and maintaining euglycemia or mild hypoglycemia with no risk of severe hypoglycemia.

On a découvert que le traitement par GLP-1 après une attaque aiguë ou une hémorragie, de préférence par administration intraveineuse, peut constituer un traitement idéal, parce qu'il offre un moyen d'optimiser la sécrétion d'insuline, d'accroître l'anabolisme cérébral, d'améliorer l'efficacité de l'insuline en supprimant le glucagon, et de maintenir l'euglycémie ou une hypoglycémie faible, sans risque d'hypoglycémie grave.

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