C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/00 (2006.01) C12N 9/02 (2006.01) C12N 9/10 (2006.01) C12N 9/88 (2006.01) C12P 7/22 (2006.01)
Patent
CA 2598414
A recombinant micro-organism producing resveratrol by a pathway in which phenylalanine ammonia lyase (PAL) produces trans-cinnamic acid from phenylalanine, cinnamate 4- hydroxylase (C4H) produces 4-coumaric acid from said trans- cinnamic acid, 4-coumarate-CoA ligase (4CL) produces 4- coumaroyl CoA from said 4-coumaric acid, and resveratrol synthase (VST) produces said resveratrol from said 4- coumaroyl CoA, or in which L-phenylalanine- or tyrosine- ammonia lyase (PAL/TAL) produces 4-coumaric acid, 4- coumarate-CoA ligase (4CL) produces 4-coumaroyl CoA from said 4-coumaric acid, and resveratrol synthase (VST) produces said resveratrol from said 4-coumaroyl CoA. The micro-organism may be a yeast, fungus or bacterium including Saccharomyces cerevisiae, E. coli, Lactococcus lactis, Aspergillus niger, or Aspergillus oryzae.
Microorganisme recombiné produisant du resvératrol par une voie dans laquelle la phénylalanine ammonia-lyase (PAL) produit de l'acide trans-cinnamique à partir de phénylalanine, la cinnamate 4-hydroxylase (C4H) produit de l'acide 4-coumarique à partir dudit acide trans-cinnamique, la 4-coumarate-CoA ligase (4CL) produit de la 4-coumaroyl-CoA à partir dudit acide 4-coumarique et la resvératrol synthétase (VST) produit ledit resvératrol à partir de ladite 4-coumaroyl-CoA ou bien dans laquelle la L-phénylalanine ou tyrosine ammonia-lyase (PAL/TAL) produit de l'acide 4-coumarique, la 4-coumarate-CoA ligase (4CL) produit de la 4-coumaroyl-CoA à partir dudit acide 4-coumarique et la resvératrol synthétase (VST) produit ledit resvératrol à partir de ladite 4-coumaroyl-CoA. Le microorganisme peut être une levure, un champignon ou une bactérie dont Saccharomyces cerevisiae, E. coli, Lactococcus lactis, Aspergillus niger ou Aspergillus oryzae.
Forster Jochen
Katz Michael
Nielsen Jens Bredal
Smits Hans Peter
Deeth Williams Wall Llp
Fluxome Sciences A/s
LandOfFree
Metabolically engineered cells for the production of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Metabolically engineered cells for the production of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Metabolically engineered cells for the production of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1433805