C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 271/56 (2006.01) A61K 31/27 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2674359
Pharmacological inhibition of fatty acid amide hydrolase (FAAH) activity leads to increased levels of fatty acid amides Esters of alkylcarbamic acids are disclosed that are inhibitors of FAAH activity. Compounds disclosed herein inhibit FAAH activity. Described herein are processes for the preparation of esters of alkylcarbamic acid compounds, compositions that include them, and methods of use thereof
L'invention concerne l'inhibition pharmacologique d'une activité hydrolase d'amides d'acide gras (FAAH) menant à des niveaux accrus d'esters d'amides d'acide gras d'acides alkylcarbamiques inhibiteurs d'activité FAAH. Des composés décrits ici inhibent une activité FAAH. Sont décrits ici des processus pour la préparation d'esters de composés d'acide alkylcarbamique, des compositions les comprenant, et leurs procédés d'utilisation.
Compton Timothy R.
Dasse Olivier
Parrott Jeff A.
Putman David
Fetherstonhaugh & Co.
N.v. Organon
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