Metabolites of certain [1,4]diazepino[6,7,1-ij]quinoline...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/06 (2006.01) A61K 31/551 (2006.01) A61K 31/7024 (2006.01) A61K 31/704 (2006.01) C07H 15/26 (2006.01)

Patent

CA 2586122

The invention relates to metabolites of certain [1,4]diazepino[6,7,1- i~]quinoline derivatives and methods of preparation and use thereof. Specifically, the invention relates to compounds of formula I wherein the various substituents are defined herein. The invention also provides pharmaceutical compositions including compounds of formula I, methods of making such compounds, and methods of using such compounds.

Cette invention concerne des métabolites de certains dérivés de [1,4]diazepino[6,7,1-i~]quinoline, ainsi que des procédés permettant de les préparer et de les utiliser. Plus spécifiquement, cette invention concerne des composés représentés par la formule I, les divers substituants étant définis dans la description. Cette invention concerne également des compositions pharmaceutiques contenant les composés représentés par la formule I, des procédés permettant de préparer de tels composés ainsi que des procédés permettant de les utiliser.

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