Metabolites of (thio)carbamoyl-cyclohexane derivatives

Details Metabolites of (thio)carbamoyl-cyclohexane derivatives Metabolites of (thio)carbamoyl-cyclohexane derivatives

C - Chemistry, Metallurgy

07

D

C07D 295/135 (2006.01) A61K 31/495 (2006.01)

Patent

CA 2684149

The present invention relates to metabolites of(thio)-carbamoyl cyclohexane derivatives, particularly, metabolites of trans-4-{2-[4-(2,3-dichlorophenyl)-piperazin-1-yl]-ethyl}-N,N- dimemylcarbamoyl-cyclohexylamine and pharmaceutically acceptable salts thereof, to pharmaceutical compositions containing the same and to their use in the treatment and/or prevention of a conditions which requires modulation of dopamine receptors.

La présente invention concerne des métabolites de dérivés de (thio)-carbamoyl-cyclohexane, en particulier des métabolites de la trans-4-{2-[4-(2,3-dichlorophényl)-piperazin-1-yl]-éthyl}-N,N-diméthylcarbamoyl-cyclohexylamine) et leurs sels acceptables sur le plan pharmaceutique, des compositions pharmaceutiques en contenant et leur utilisation en vue du traitement et/ou de la prévention d'une affection exigeant une modulation des récepteurs de la dopamine.

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