Metabotropic glutamate receptor antagonists for treating...

A - Human Necessities – 61 – K

Patent

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A61K 31/44 (2006.01) A61K 31/00 (2006.01) A61K 31/197 (2006.01) A61K 45/00 (2006.01) A61K 45/06 (2006.01) A61P 25/30 (2006.01) A61P 25/32 (2006.01) A61P 25/34 (2006.01) A61P 25/36 (2006.01) G01N 33/94 (2006.01)

Patent

CA 2402341

An antagonist of the metabotropic glutamate receptor 5(mGluR5) is useful in tolerance or dependence therapy. Such an antagonist can therefore be used in the treatment of substance tolerance or dependence, bulimia nervosa, anorexia nervosa, gambling dependence, sex dependence or obsessive compulsive disorders.

L'invention concerne un antagoniste du récepteur 5(mGluR5) de glutamate métabotrope utile dans le traitement d'accoutumance ou de dépendance. On peut donc utiliser un tel antagoniste dans le traitement de la tolérance ou de la dépendance à une substance, de boulimie, d'anorexie, de dépendance au jeu, de dépendance sexuelle ou de troubles obsessionnels compulsifs.

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