Metal chelate conjugated monoclonal antibodies

C - Chemistry – Metallurgy – 07 – K

Patent

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167/139

C07K 16/30 (2006.01) A61K 39/395 (2006.01) A61K 51/10 (2006.01) C07K 16/10 (2006.01) C07K 16/18 (2006.01)

Patent

CA 1225930

METAL CHELATE CONJUGATED MONOCLONAL ANTIBODIES ABSTRACT Methods of manufacturing and purifying metal chelate conjugated monoclonal antibodies are described, wherein the chelated metal emits alpha radiation. The conjugates are suited for therapeutic uses being substantially free of nonchelated radiometal.

429760

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